[Clin Infect Dis 2009;48:503-35.]
- Usually associated with foreign body in urinary tract. Removal of urinary catheter or stent results in ~40% eradication of candiduria but only 20% eradication if catheter/stent subsequently reinserted.
- Persistent candiduria in immunocompromised patients warrants ultrasound or CT of kidney.
- Bladder irrigation with amphotericin B has been used to treat candidal cystitis but does not treat infections beyond the bladder and has a high relapse rate. May be useful for fluconazole resistant Candida species, e.g. C. krusei or C. glabrata.
- Use of echinocandins should be avoided for candiduria due to poor urinary concentrations and limited clinical data.
|Treatment not recommended unless high risk|
|Fluconazole||200mg (3mg/kg) PO daily||14 days|
|Amphotericin B||0.3-0.6mg/kg IV daily||1-7 days|
|Fluconazole||200-400mg (3-6mg/kg) PO daily||14 days|
|Amphotericin B||0.5-0.7mg/kg IV daily||14 days|