Extracutaneous
Usual PathogensSporothrix schenckii
Osteoarticular
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Itraconazole | 200mg PO bid | 12 months |
Pulmonary - severe
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Amphotericin B | 0.7-1mg/kg IV daily | Until response then switch to itraconazole for total of 12 months |
Pulmonary - less severe
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Itraconazole | 200mg PO bid | 12 months |
Meningeal or disseminated
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Amphotericin B | 0.7-1mg/kg IV daily | Until response then switch to itraconazole for total of 12 months |