Oropharyngeal candidiasis
[Clin Infect Dis 2009;48:503-35.]
- Screen for HIV unless:
- infant
- known immunodeficiency/ immunosuppression
- recent use of inhaled steroids.
- For immunosuppressed patients, fluconazole 200mg/ day is recommended. Maintenance therapy may be necessary.
Usual Pathogens
Candida albicans
Occasionally non-C. albicans yeast
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Nystatin susp | 500,000 U (5mL) qid | 7-14 days |
| or | ||
| Clotrimazole vag insert used orally | 100mg PO daily | 7-14 days |
Alternative
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Fluconazole | 100-200mg (3mg/kg) PO daily | 7-14 days |
Infants (Thrush)
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Nystatin | 100,000 U (1mL) qid | 7-10 days |