Allergic bronchopulmonary aspergillosis (ABPA)

- Allergic response to fungal hyphae in bronchial tree, manifesting as sinusitis and asthma and characterized by wheezing and pulmonary infiltrates, leading to bronchiectasis and fibrosis.

- Corticosteroids are primary therapy.

 
Usual Pathogens

Aspergillus spp

 

Empiric Therapy Dose Duration
Itraconazole 200mg PO bid 3-6 months

Alternative

Empiric Therapy Dose Duration
Voriconazole 200mg PO bid 3-6 months