Carbapenems

Antimicrobial Normal Adult Dose Dose and Interval Adjustment for Renal Impairment
Creatinine Clearance (mL/min)
>50 10 - 50 <10 (Anuric)
Ertapenem 1g IV daily 1g daily ≤ 30mL/min: 500mg daily
Imipenem 500mg IV q6h q6h q8-12h 250-500mg q12h
Meropenem 500mg IV q6h q6h 26-50mL/min: q8h q24h
      10-25mL/min: q12h  
  1-2g IV q8h q8h q12h 500mg q24h