Prophylaxis of sexually transmitted infections

Neisseria gonorrhoeae

Prophylaxis Dose & Duration
Cefixime 800mg PO x 1 dose
or  
Ceftriaxone 250mg IM x 1 dose

Cephalosporin/severe penicillin allergy

Prophylaxis Dose & Duration
Azithromycin 2g PO x 1 dose

Chlamydia trachomatis

Prophylaxis Dose & Duration
Azithromycin 1g PO x 1 dose
or  
Doxycycline 100mg PO bid x 7 days

Pregnancy/Lactation

Prophylaxis Dose & Duration
Amoxicillin 500mg PO tid x 7 days
or  
Azithromycin 1g PO x 1 dose

Hepatitis B virus (HBV)

Prophylaxis indicated if:

  • Assailant infected with HBV
  • Requested by victim
  • Victim unlikely to return for follow up
  • Hepatitis B immunization < 3 doses
Prophylaxis Dose & Duration
Hepatitis B immunoglobulin (HBIG) 0.06mL/kg IM once
+  
Hepatitis B vaccine Doses at 0, 1, 6 mos

HIV

If assailant known to be HIV positive or at high risk for HIV, e.g. known injection drug use or MSM, offer HIV post exposure prophylaxis in consultation with Regional Public Health and Infectious Diseases.