Vancomycin Monitoring Guidelines

• Routine monitoring of vancomycin levels is NOT recommended because there is:
  • little literature evidence to support it
  • no clear evidence that nephrotoxicity and ototoxicity associated with vancomycin can be prevented by strict adherence to specific concentration ranges.
• Peak (post) levels are NOT needed because:

  • they have not been correlated with improvements in clinical outcome.

  • vancomycin has slow distribution into peripheral tissues making it difficult to identify the true peak.