Rubella

Potential Effect on Fetus

  • Fetal loss
  • Congenital Syndrome especially:
    • hearing loss
    • congenital heart failure
    • cataracts
    • thrombocytopenia/purpura

Rate of Perinatal Transmission

  • 1st trimester – 67-85% (infection in 1st trimester associated with more severe fetal infection)
  • 11-16 weeks – 55%
  • > 16 weeks – 45%

Maternal Screening

- Routine Rubella IgG performed in 1st trimester.

- If maternal rubella suspected, perform Rubella IgM.

Prevention

- Vaccination before or after pregnancy (not during).

- In acute infection – droplet precautions.

- In neonatal infection acquired congenitally, use contact precautions for at least 1 year unless nasopharyngeal and urine cultures repeatedly negative after 3 months.