Peritonsillar abscess

- Collection of pus between capsule of palatine tonsil and the pharyngeal muscles typically preceded by tonsillitis or pharyngitis

Differential diagnosis:

- Epiglottitis, retropharyngeal abscess

- Parapharyngeal space abscess

Management:

- Prompt surgical intervention if airway compromise - needle aspiration/incision and drainage

 

Usual Pathogens

Frequently polymicrobial:

Group A Strep

S. anginosus group

S. aureus/MRSA

oral anaerobes

 

Rarely:

Haemophilus spp

 

Empiric Therapy Dose Duration
Amoxicillin-clavulanate 1.2g IV q8h 10 days
If MRSA risk factors, add:    
Vancomycin 15mg/kg IV q12h 10 days

Amoxicillin allergy

Empiric Therapy Dose Duration
Cefuroxime 1.5g IV q8h 10 days
+    
Metronidazole 500mg IV q12h  
If MRSA risk factors, add:    
Vancomycin 15mg/kg IV q12h 10 days