N. meningitidis
- Empiric use of dexamethasone should be discontinued.
- For prophylaxis of N. meningitidis in patient, if he/she has not received at least one dose of ceftriaxone, and in close contacts, see Prophylaxis for Contacts of Communicable Diseases.
Pen MIC ≤ 0.1 µg/mL
| Therapy |
Dose |
Duration |
| Penicillin G |
4MU IV q4h |
5-7 days |
| or |
|
|
| Ampicillin |
2g IV q4h |
5-7 days |
Alternative
| Therapy |
Dose |
Duration |
| Ceftriaxone |
2g IV q12h |
5-7 days |
Pen MIC > 0.1 µg/mL
| Therapy |
Dose |
Duration |
| Ceftriaxone |
2g IV q12h |
5-7 days |
Alternative
| Therapy |
Dose |
Duration |
| Meropenem |
2g IV q8h |
5-7 days |
| or |
|
|
| Ciprofloxacin |
400mg IV q8-12h/750mg PO bid |
5-7 days |
| or |
|
|
| Chloramphenicol |
12.5mg/kg IV q6h (max 4g/day) |
5-7 days |
