H. influenzae

- Continue use of dexamethasone x 4 days.

- For prophylaxis of H. influenzae in patient, if he/she has not received at least one dose of ceftriaxone, and in close contacts, see Prophylaxis for Contacts of Communicable Diseases.

 

Therapy

Dose

Duration
Dexamethasone 10mg IV q6h 4 days

PLUS

Ampicillin-susceptible MIC ≤ 0.5 µg/mL

Therapy

Dose

Duration
Ampicillin 2g IV q4h 7-10 days

Ampicillin-resistant - MIC >  0.5 µg/mL

Therapy Dose Duration
Ceftriaxone 2g IV q12h 7-10 days

Alternative or ceftriaxone MIC > 0.125 µg/mL

Therapy

Dose

Duration
Meropenem (providing MIC ≤ 0.25 µg/mL) 2g IV q8h 7-10 days
or    
Ciprofloxacin
400mg IV q8-12h/750mgPO bid 7-10 days
or    
Chloramphenicol 12.5mg/kg IV q6h (max 4g/day) 7-10 days