Enterobacterales
| Therapy | Dose | Duration |
|---|---|---|
| TMP/SMX | 1 DS tab PO bid |
One- or two-stage exchange: 4-6 weeks Debridement and implant retention (DAIR): 12 weeks |
| or |
|
|
| Ciprofloxacin | 750mg PO bid |
One- or two-stage exchange: 4-6 weeks Debridement and implant retention (DAIR): 12 weeks |
| or | ||
| Ceftriaxone | 2g IV daily |
One- or two-stage exchange: 4-6 weeks Debridement and implant retention (DAIR): 12 weeks |
Ceftriaxone & Ciprofloxacin resistant organism
| Therapy | Dose | Duration |
|---|---|---|
| TMP/SMX | 1 DS tab PO bid |
One- or two-stage exchange: 4-6 weeks Debridement and implant retention (DAIR): 12 weeks |
| or |
|
|
| Ertapenem | 1g IV daily |
One- or two-stage exchange: 4-6 weeks Debridement and implant retention (DAIR): 12 weeks |