Enterococcus spp
Amp S, Gent synergy S
| Therapy | Dose | Duration |
|---|---|---|
| [Ampicillin | 2g IV q4h | 4 weeks |
| + | ||
| Gentamicin] | 1mg/kg IV q8-12h | 4 weeks |
| or | ||
| [Ampicillin | 2g IV q4h | 6 weeks |
| + | ||
| Ceftriaxone] | 2g IV q12h | 6 weeks |
Amp S, Gent synergy R, Strep synergy S
| Therapy | Dose | Duration |
|---|---|---|
| [Ampicillin | 2g IV q4h | 6 weeks |
| + | ||
| Ceftriaxone] | 2g IV q12h | 6 weeks |
| or | ||
| [Ampicillin | 2g IV q4h | 4 weeks |
| + | ||
| Streptomycin] | 7.5mg/kg IV/IM q12h | 4 weeks |
Amp S, Gent/Strep synergy R
| Therapy | Dose | Duration |
|---|---|---|
| [Ampicillin | 2g IV q4h | 6 weeks |
| + | ||
| Ceftriaxone] | 2g IV q12h | 6 weeks |
| or | ||
| Ampicillin | 3g IV q4h | 8-12 weeks |
Amp R, Gent synergy S - high level ampicillin resistance MIC > 128µg/mL
| Therapy | Dose | Duration |
|---|---|---|
| Vancomycin | 15mg/kg IV q8-12h | 6 weeks |
| + | ||
| Gentamicin | 1mg/kg IV q8-12h | 6 weeks |
Amp R, Gent synergy S - low level ampicillin resistance MIC 16-64µg/mL
| Therapy | Dose | Duration |
|---|---|---|
| [Vancomycin | 15mg/kg IV q8-12h | 6 weeks |
| + | ||
| Gentamicin] | 1mg/kg IV q8-12h | 6 weeks |
| or | ||
| [Ampicillin | 3g IV q4h | ≥ 6 weeks |
| + | ||
| Gentamicin] | 1mg/kg IV q8-12h | 4-6 weeks |
Amp R, Vanco R MIC > 4µg/mL, Gent/Strep synergy R
Consult Infectious Diseases.
| Therapy | Dose | Duration |
|---|---|---|
| Linezolid | 600mg IV/PO q12h | ≥ 8 weeks |
| or | ||
| [Daptomycin | 10mg/kg IV daily | ≥ 8 weeks |
| + | ||
| Ampicillin] | 2g IV q4h | ≥ 8 weeks |