Trichomoniasis

Canadian Guidelines on Sexually Transmitted Infections - Vaginal Discharge

 

- Trichomoniasis may be associated with:

  • premature rupture of membranes (PROM)

  • preterm birth

  • low birth weight

  • HIV transmission

  • PID

- Treat all cases and their sexual partners regardless of symptoms.

- For metronidazole allergy/intolerance, see Am J Obstet Gynecol 2008;198:370.e1-7 for incremental dosing protocol for metronidazole.

- Some (~5%) metronidazole resistance.

 
Usual Pathogens

T. vaginalis

Non-Pregnant/Not Breastfeeding Women

Empiric Therapy Dose Duration
Metronidazole 500mg PO bid 7 days
Alternative    
Metronidazole 2g PO 1 dose

Failure/recurrence

Empiric Therapy Dose Duration
Metronidazole 500mg PO bid or 7 days
  2g PO daily 3-5 days

Pregnant/Breastfeeding Women

Empiric Therapy Dose Duration
Metronidazole 2g PO 1 dose