S. aureus, methicillin resistant (MRSA)

Consult Infectious Diseases

 

Empiric Therapy

Intermittent Dosing

1 exchange daily with dwell time at least 6h

Continuous Dosing

(per each L bag)

Duration
Vancomycin IP

15-30mg/kg q5-7 days for CAPD

15mg/kg q4 days for APD

20-25mg/kg LD then 25mg/L MD

21 days
Strongly recommend catheter removal for refractory peritonitis.

Treat for 14 days after catheter removal.

+/-      
Rifampin PO

450mg PO daily if weight <50kg,

600mg PO daily if weight ≥50kg

450mg PO daily if weight <50kg,

600mg PO daily if weight ≥50kg

 
  Paediatric: 10-20mg/kg/d PO div bid    

 

APD = automated peritoneal dialysis

CAPD = continuous ambulatory peritoneal dialysis

IP = intraperitoneally

LD = loading dose

MD = maintenance dose