Enterobacterales

- Consult Infectious Diseases.

- Valve replacement often necessary depending on organism.

 

Therapy Dose Duration
Ceftriaxone 2g IV daily ≥ 6 weeks
+    
[Gentamicin 1.5-2mg/kg IV q8h ≥ 6 weeks
or    
Ciprofloxacin] 750mg PO bid or  
  400mg IV q8-12h  
ESBL/AmpC producing organism    
[Imipenem 500mg IV q6h ≥ 6 weeks
or    
Meropenem] 500mg IV q6h or ≥ 6 weeks
  1g IV q8h  
+    
[Gentamicin 1.5-2mg/kg IV q8h ≥ 6 weeks
or    
Ciprofloxacin] 750mg PO bid or  
  400mg IV q8-12h