What's New
Updated May 2022:
- Viral keratitis in Ophthalmic Infections section
Updated March 2022:
- Chorioamnionitis empiric therapy section
Updated February 2022:
- COVID-19 Treatment Guidelines
Updated January 2022:
- Adult Bone & Joint Infection empiric therapy section
- Culture-directed Prosthetic Joint Infection section
Updated December 2021:
- Pediatric Bone & Joint Infection empiric therapy section
- Pediatric Sepsis without a focus and Sepsis empiric therapy sections
Updated November 2021:
- Ophthalmic Infections: Blepharitis
Updated October 2021:
- COVID-19 section
- Treatment Recommendations, Adult, Urinary Tract, Asymptomatic Bacteriuria and Cystitis in Pregnancy – removed fosfomycin as it crosses the placenta and risk-benefit must be considered, and single dose regimens are no longer recommended in pregnancy for cystitis
Dental: please note greatly diminished role, or exclusion, of clindamycin; and addition of cefuroxime axetil as the preferred option in truly penicillin-allergic patients
- Antimicrobial Prophylaxis in Dentistry
- Recommended Empiric Therapy of Selected Dental Infections
Updated June 2021:
- Adult Clostridioides difficile infection (CDI) – oral vancomycin prophylaxis for high risk patients with recurrent CDI
- Prophylaxis for infective endocarditis
Updated May 2021:
- Cefaclor (discontinued in Canada) added to β-lactam cross-reactivity chart for patients who report an allergy in the past
- Changed duration of therapy for mild to moderate community-acquired pneumonia (CAP) to 3 days provided clinical stability criteria are met
- Changed duration of therapy for hand and wrist septic arthritis with surgical drainage to 2 weeks
- Adult central nervous system empiric therapy recommendations
- Adult meningitis culture-directed therapy recommendations
- Addition of culture-directed medical device-associated meningitis/ventriculitis section
Updated March 2021:
- Update of pediatric and adult Genital empiric therapy sections
Updated January 2021:
- Neonatal/pediatric central nervous system empiric therapy recommendations
- Spectrum of activity of doxycycline, macrolides, and quinolones for Mycoplasma and Ureaplasma spp