Gram negative risk factors:
-
bronchiectasis
-
immunosuppression
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Piperacillin-tazobactam | 4.5g IV q6h | 7-10 days |
| + | ||
| Azithromycin | 500mg IV/PO daily | 3 days |
| +/- | ||
| Vancomycin | 25-30mg/kg IV once then 15mg/kg IV q8-12h | 7-10 days |
Penicillin allergy
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Ciprofloxacin | 400mg IV q12h/500-750mg PO bid | 7-10 days |
| + | ||
| Vancomycin | 25-30mg/kg IV once then 15mg/kg IV q8-12h |