Kytococcus spp

  • K. schoeteri
  • K. sedentarius

Gram Stain

  • Gram positive cocci in tetrads and clusters (aerobic)

Clinical Significance

These organisms are found in the environment and are considered saprophytes of skin and mucous membranes.

 

They have been associated with central nervous system infections, septic arthritis, pneumonia, hepatic abscesses, catheter related peritonitis, bacteremia and endocarditis (typically prosthetic valve/medical device related).

K. sedentarius causes pitted keratolysis - a malodorous erosive condition of soles of the feet associated with prolonged occlusive footwear.

 

Usual Susceptibility Pattern

These organisms are generally susceptible to vancomycin, linezolid, tetracyclines, imipenem, quinolones, and rifampin.

They are resistant to penicillin, cloxacillin, and cephalosporins.

 

Macrolide susceptibility is variable.

 

Empiric Therapy
Vancomycin
For medical device related infections, add:
Rifampin
+/-

Gentamicin