Intravenous drug use
- Predilection for sternoclavicular or sacroiliac joint, ribs, vertebrae, long bones.
- Must rule out endocarditis.
Usual Pathogens
S. aureus/MRSA
Streptococcus spp
Occasionally:
P. aeruginosa
Salmonella spp
Serratia spp
Candida spp (consult ID)
Anaerobes
Rare:
M. tuberculosis (consult ID)
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Vancomycin | 15mg/kg IV q12h | 6 weeks |
| + | ||
| Ceftriaxone | 1-2g IV daily |