Secondary prophylaxis may be considered in high risk patients: ascitic fluid protein <10-15g/L plus at least one of:

  • bilirubin > 30mg/L
  • platelets < 98 x 109/L
  • serum creatinine >100µmol/L
  • sodium ≤130mmol/L
  • Child-Pugh score ≥ 9 points.