Facial

Usual Pathogens

Group A Streptococci
S. aureus

Mild

Empiric Therapy

Dose

Duration
Cloxacillin 500mg PO qid 5 days
or    
Cephalexin 500-1000mg PO qid

5 days

Penicillin and cephalexin allergy

Empiric Therapy Dose Duration
Cefuroxime axetil 500mg PO bid

5 days

Cefuroxime allergy

Empiric Therapy Dose Duration
Clindamycin 300mg PO qid

5 days

 

Moderate-severe

Empiric Therapy

Dose

Duration
Cloxacillin 2g IV q6h 5-10 days
or    
Cefazolin 2g IV q8h

5-10 days

Penicillin and cefazolin allergy

Empiric Therapy Dose Duration
Ceftriaxone 2g IV daily

5-10 days

Ceftriaxone allergy

Empiric Therapy

Dose

Duration
Clindamycin IV/PO 600mg IV q8h/300mg PO qid

5-10 days