Enterococcus spp, vancomycin-resistant
| Empiric Therapy |
Intermittent Dosing 1 exchange daily with dwell time at least 6h |
Continuous Dosing (per each L bag) |
Duration |
|---|---|---|---|
| Based on susceptibility results: | |||
| Ampicillin-susceptible: |
|||
| Amoxicillin PO | 500mg PO tid | 500mg PO tid |
21 days Strongly recommend catheter removal for refractory peritonitis. Treat for 14 days after catheter removal. |
| Ampicillin-resistant: | |||
| Linezolid PO/IV |
600mg PO/IV bid for 48h, then 300mg PO/IV bid |
600mg PO/IV bid for 48h, then 300mg PO/IV bid |
21 days Strongly recommend catheter removal for refractory peritonitis. Treat for 14 days after catheter removal. |
| or | |||
| Daptomycin IP | 300mg IP once per day |
100mg/L LD then 20mg/L MD |
21 days Strongly recommend catheter removal for refractory peritonitis. Treat for 14 days after catheter removal. |
IP = intraperitoneally
LD = loading dose
MD = maintenance dose