Doxycycline

Predictable Activity

Actinobacillus spp

Actinobaculum spp
Actinotignum spp
Aeromonas spp
Aggregatibacter spp
Arcanobacterium haemolyticum

Bacillus cereus group

Bartonella spp
Borrelia burgdorferi
Campylobacter spp
Capnocytophaga spp

Cardiobacterium spp

Chlamydia spp
Coxiella burnetii

Dysgonomonas spp
Eikenella spp
Francisella tularensis

Gardnerella spp
Haemophilus influenzae
Haemophilus parainfluenzae

Kingella spp
Legionella spp
Leptospira spp

Mannheimia spp

Micrococcus spp

Moraxella catarrhalis
Mycobacterium abscessus
Mycobacterium chelonae
Mycobacterium fortuitum
Mycoplasma pneumoniae (new name Mycoplasmoides pneumoniae)

Neisseria spp (animal origin)

Neisseria meningitidis

Pasteurella spp

Plesiomonas spp
Rickettsia spp

Rothia spp
Staphylococcus aureus (MSSA, MRSA)

Staphylococcus saprophyticus
Treponema pallidum
Tropheryma whippleii
Trueperella spp

Ureaplasma spp

Vibrio spp
Yersinia spp

Unpredictable Activity

Abiotrophia spp

Acinetobacter spp
Actinomyces spp
Aerobic Gram negative bacilli – nonfermenters
Aerococcus spp
Bacillus spp
Bergeyella zoohelcum
Brucella spp
Burkholderia spp
Chryseobacterium spp
Citrobacter freundii complex
Coagulase negative Staphylococci (CoNS)

Corynebacterium spp
Cutibacterium acnes
Enterobacter spp
Enterococcus spp

Erysipelothrix spp

Esherichia coli

Gemella spp

Granulicatella spp

Group A Streptococci

Helicobacter pylori
Klebsiella oxytoca
Klebsiella pneumoniae

Leuconostoc spp

Listeria spp

Mycoplasma genitalium (new name Mycoplasmoides genitalium)

Mycoplasma hominis (new name Metamycoplasma hominis)

Neisseria gonorrheae

Neisseria spp (oral  flora)

Nocardia spp
Raoultella spp

Shigella spp
Staphylococcus lugdunensis
Stenotrophomonas maltophilia

Streptococcus anginosus group

Streptococcus bovis group

Streptococcus pneumoniae
Streptococcus spp (zoonotic)

No/Insufficient Activity

Anaerobes

Group B,C,G Streptococci

Listeria monocytogenes
Morganella morganii
Proteus mirabilis
Proteus vulgaris complex

Providencia spp
Pseudomonas aeruginosa
Pseudomonas spp
Salmonella spp
Serratia spp