Brain abscess

[Clin Microbiol Infect 2023;1-71]


- Surgical therapy usually required with either stereotactic aspiration or open drainage. Send fluid/tissue for Gram stain and culture.

- Rule out: sinusitis, otitis, dental infection, endocarditis, congenital heart disease, lung abscess.

- If multiple abscesses, blood cultures are recommended before antibiotics.

Usual Pathogens

Viridans Group Streptococci including Streptococcus anginosus group (S. anginosus, S. constellatus, S. intermedius)
S. aureus/MRSA


Empiric Therapy Dose Duration
Ceftriaxone 100mg/kg/d IV div q12h 6 weeks
Metronidazole 30mg/kg/d IV div q8h  
Vancomycin 60mg/kg/d IV div q6h