Fistulas/Discontinuous bowel segments
Common Pathogens
Enterobacteriaceae
Anaerobes
| Regimen(s) of Choice See General Principles and Pre-Op Antibiotic Administration and Intraoperative Antibiotic Administration | ||
|---|---|---|
| Cefazolin | 2g IV | x 1 pre-op dose |
| + | ||
| Metronidazole | 500mg IV | x 1 pre-op dose |
| Alternative Regimens if allergy to cefazolin, or severe non-IgE-mediated reaction to any β-lactam (interstitial nephritis, hepatitis, hemolytic anemia, serum sickness, severe cutaneous reactions [e.g. SJS, TEN, DRESS]) | ||
|---|---|---|
| [Gentamicin | 1.5mg/kg IV | x 1 pre-op dose |
| + | ||
| Clindamycin] | 600mg IV | x 1 pre-op dose |
| or | ||
| [Gentamicin | 1.5mg/kg IV | x 1 pre-op dose |
| + | ||
| Metronidazole] | 500mg IV | x 1 pre-op dose |